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Sensory Neuropathy Complete Antibody Panel
Test Code15977
CPT Codes
84181, 86255, 82595, 86334, 82784 (x3), 86431, 86235 (x2), 86038, 86021 (x2), 86036, 86364, 83520 (x3)
Includes
ANA Screen, IFA with Reflex to Titer and Pattern, IFA
If ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional charge (CPT code(s): 86039).
ANCA Screen with Reflex to ANCA Titer
If ANCA Screen is positive, then C-ANCA Titer and/or P-ANCA Titer, and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86037 for each titer performed).
Cryoglobulin Screen with Reflex to Cryoglobulin Reflex
If Cryoglobulin Screen is positive, then Cryoglobulin Reflex will be performed at an additional charge (CPT code(s): 86334, 86329).
Ganglioside GD1b Antibodies (IgG, IgM), EIA
Ganglioside GQ1b Antibody (IgG), EIA
Hu Antibody Screen with Reflex to Titer and Western Blot
If Hu Antibody Screen, IFA is positive, then Hu Antibody, WB will be performed at an additional charge (CPT code(s): 84181).
If Hu Antibody, WB is positive, then Hu Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
Immunofixation (IFE), Serum
Immunoglobulins (IgG, IgA and IgM)
If IgA (Immunoglobulin A) is abnormal, then Tissue Transglutaminase (tTG) Antibody (IgG) will be performed at an additional charge (CPT code(s): 86364).
Myelin Associated Glycoprotein (MAG) Antibody, with Reflex to MAG-SGPG and MAG, EIA
If MAG Antibody (IgM), WB is positive, then MAG-SGPG Antibody (IgM), EIA and MAG Antibody (IgM), EIA, will be performed at an additional charge (CPT code(s): 83520 x2).
Myeloperoxidase Antibody (MPO)
Proteinase-3 Antibody
Rheumatoid Factor
Sjögren's Antibodies (SS-A, SS-B)
Tissue Transglutaminase (tTG) Antibody (IgA)
If Tissue Transglutaminase (tTG) Antibody (IgA) is detected (≥15.0 U/mL), then Endomysial Antibody Screen (IgA) with Reflex to Titer will be performed at an additional charge (CPT code(s): 86231).
If Endomysial Antibody Screen (IgA) is positive, then Endomysial Antibody Titer will be performed at an additional charge (CPT code(s): 86231).
If ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional charge (CPT code(s): 86039).
ANCA Screen with Reflex to ANCA Titer
If ANCA Screen is positive, then C-ANCA Titer and/or P-ANCA Titer, and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86037 for each titer performed).
Cryoglobulin Screen with Reflex to Cryoglobulin Reflex
If Cryoglobulin Screen is positive, then Cryoglobulin Reflex will be performed at an additional charge (CPT code(s): 86334, 86329).
Ganglioside GD1b Antibodies (IgG, IgM), EIA
Ganglioside GQ1b Antibody (IgG), EIA
Hu Antibody Screen with Reflex to Titer and Western Blot
If Hu Antibody Screen, IFA is positive, then Hu Antibody, WB will be performed at an additional charge (CPT code(s): 84181).
If Hu Antibody, WB is positive, then Hu Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
Immunofixation (IFE), Serum
Immunoglobulins (IgG, IgA and IgM)
If IgA (Immunoglobulin A) is abnormal, then Tissue Transglutaminase (tTG) Antibody (IgG) will be performed at an additional charge (CPT code(s): 86364).
Myelin Associated Glycoprotein (MAG) Antibody, with Reflex to MAG-SGPG and MAG, EIA
If MAG Antibody (IgM), WB is positive, then MAG-SGPG Antibody (IgM), EIA and MAG Antibody (IgM), EIA, will be performed at an additional charge (CPT code(s): 83520 x2).
Myeloperoxidase Antibody (MPO)
Proteinase-3 Antibody
Rheumatoid Factor
Sjögren's Antibodies (SS-A, SS-B)
Tissue Transglutaminase (tTG) Antibody (IgA)
If Tissue Transglutaminase (tTG) Antibody (IgA) is detected (≥15.0 U/mL), then Endomysial Antibody Screen (IgA) with Reflex to Titer will be performed at an additional charge (CPT code(s): 86231).
If Endomysial Antibody Screen (IgA) is positive, then Endomysial Antibody Titer will be performed at an additional charge (CPT code(s): 86231).
Preferred Specimen
18.9 mL serum collected in a red-top tubes (no gel)
Patient Preparation
Overnight fasting is required
Minimum Volume
7.3 mL
Instructions
See individual assays for shipping temperatures and collection instructions.
*** Multiple tubes required for testing** - See note ***
Note: Cryoglobulin Screen and reflex: Collect 20 mL of fasting whole blood specimen in a red-top tube (no gel). 10 mL serum required: 3.5 mL minimum.
Allow serum sample to clot for one (1) hour in a 37°C water bath, oven, incubator, or heat block. After clotting, centrifuge the specimen for 10 minutes at 1600 RCF(G) utilizing one of the 3 options below:
1) In a "warm" centrifuge at 37°C
2) In a bench-top centrifuge placed in a "warm room" at 37°C
3) At room temperature, in a bench-top centrifuge prewarmed by running it for 10 minutes at 1600 RCF(G).
After centrifuging, decant serum into a screw-cap vial Transport at room temperature in separate transport tube clearly marked "CRYO" since sample will not be viable for other testing.
Avoid hemolysis. Avoid freezing and thawing. Avoid lipemia.
*** Multiple tubes required for testing** - See note ***
Note: Cryoglobulin Screen and reflex: Collect 20 mL of fasting whole blood specimen in a red-top tube (no gel). 10 mL serum required: 3.5 mL minimum.
Allow serum sample to clot for one (1) hour in a 37°C water bath, oven, incubator, or heat block. After clotting, centrifuge the specimen for 10 minutes at 1600 RCF(G) utilizing one of the 3 options below:
1) In a "warm" centrifuge at 37°C
2) In a bench-top centrifuge placed in a "warm room" at 37°C
3) At room temperature, in a bench-top centrifuge prewarmed by running it for 10 minutes at 1600 RCF(G).
After centrifuging, decant serum into a screw-cap vial Transport at room temperature in separate transport tube clearly marked "CRYO" since sample will not be viable for other testing.
Avoid hemolysis. Avoid freezing and thawing. Avoid lipemia.
Transport Temperature
See individual tests
Specimen Stability
See individual tests
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
See individual assays
Methodology
Immunoassay (IA)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
See individual assays
