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Saccharomyces cerevisiae Antibodies (ASCA) (IgG, IgA)
Test Code17609
CPT Codes
86671 (x2)
Preferred Specimen
2 mL serum
Minimum Volume
0.6 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 21 days
Frozen: 21 days
Refrigerated: 21 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia
Methodology
Immunoassay (IA)
Setup Schedule
A.M.
Clinical Significance
Antibodies to Saccharomyces cerevisiae are found in approximately 75% of patients with Crohn's disease, 15% of patients with ulcerative colitis, and 5% of the healthy population. High titers of antibody increase the likelihood of disease, specifically Crohn's disease, and are associated with more aggressive disease.
