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Ri Antibody Screen with Reflex to Titer and Western Blot, CSF
Test Code90121
CPT Codes
86255
Includes
If Ri Antibody Screen, IFA, CSF is Positive, then Ri Antibody, WB, CSF will be performed at an additional charge (CPT codes: 84181).
If Ri Antibody, WB, CSF is Positive, then Ri Antibody, Titer, CSF will be performed at an additional charge (CPT code(s): 86256).
If Ri Antibody, WB, CSF is Positive, then Ri Antibody, Titer, CSF will be performed at an additional charge (CPT code(s): 86256).
Preferred Specimen
0.8 mL CSF in a sterile screw cap container
Patient Preparation
Overnight fasting is preferred
Minimum Volume
0.5 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 8 hours
Refrigerated: 7 days
Frozen: 6 months
Refrigerated: 7 days
Frozen: 6 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature
Methodology
Immunofluorescence Assay (IFA)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Night Sets up 3 days a week.
Clinical Significance
Anti-Ri can be detected in patients with the paraneoplastic opsoclonus/myoclonus syndrome. Neoplasms most often associated with Anti-Ri include breast cancer, gynecological cancers, and small cell lung cancer.