Protein Electrophoresis, with Total Protein and Reflex to IFE, Serum

Test Code

10269

CPT Codes
84155, 84165

Includes

If abnormal banding is detected, then Immunofixation will be performed at an additional charge (CPT code(s): 86334).

Preferred Specimen

4 mL serum

Patient Preparation
Overnight fasting is preferred

Minimum Volume

2 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days
Refrigerated: 7 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Plasma

Methodology
Capillary Zone Electrophoresis • Spectrophotometry (SP)

Setup Schedule

See individual assays

Clinical Significance

Serum protein electrophoresis (SPE) is an analytical technique that provides separation of serum protein into six fractions: Albumin, Alpha-1, Alpha-2, Beta-1, Beta-2, and Gamma. Interpretation of elevation, decreased, or visual change in different fractions can be used as a diagnostic aid for a variety of different disease states and protein abnormalities, including monoclonal gammopathies (MG).

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.