A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Perforin, IHC with Interpretation

Test Code
90356


CPT Codes
88342

Preferred Specimen
Formalin fixed paraffin embedded tissue in an IHC specimen transport kit


Other Acceptable Specimens
Unstained charged (+) slides collected in IHC specimen transport kit (x5)


Instructions
Please include surgical pathology report


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinite
Refrigerated: Indefinite
Frozen: Unacceptable


Methodology
Immunohistochemistry

Setup Schedule
A.M. Sets up 5 days a week.


Report Available
Reports in 2 to 3 days.


Clinical Significance
Perforin, a protein found within cytoplasmic granules, is a marker of cytotoxic lymphocytes. It is frequently positive, along with granzyme B, in extranodal natural killer (NK) cell lymphomas, aggressive NK cell leukemias and large granular lymphocyte (LGL) leukemias. Unlike TIA1, it is negative in hepatosplenic T-cell lymphoma.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.