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PAX-5, IHC with Interpretation

Test Code
40039X


CPT Codes
88342

Preferred Specimen
Formalin-fixed, paraffin-embedded tissue in an IHC specimen transport kit


Instructions
Pathology report is required


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinite
Refrigerated: Indefinite
Frozen: Unacceptable


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Tissue in formalin


Methodology
Immunohistochemical Stain

Setup Schedule
A.M.


Clinical Significance
Pax genes are a family of developmental control genes that encode nuclear transcription factors and have been implicated in the control of mammalian development. PAX-5 is a B cell specific transcription factor that is expressed in pro B-cells, pre-B and mature B cells, and subsequently in all stages of B cell development until that plasma cell stage in which it is down regulated.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.