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Neisseria meningitidis, IgG, Vaccine Response, MAID
Test Code15903X
CPT Codes
86317 (x4)
Includes
Serotypes A, C, Y, W-135
Preferred Specimen
0.5 mL serum
Minimum Volume
0.3 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Methodology
Multi-Analyte Immunodetection (MAID)
Setup Schedule
Set up: Tue; Report available: 1-7 days
Clinical Significance
This assay measures serum IgG antibodies recognizing polysaccharide antigens from the four Neisseria meningitidis serogroups included in the licensed meningococcal vaccine. The meningococcal vaccine response is best evaluated by testing pre-vaccination and post-vaccination samples in parallel. A two-fold or greater increase for at least two serogroups is expected when comparing post-vaccination to pre-vaccination results. N. Meningitidis IgG levels peak approximately one month post-vaccination, but decline markedly by two years.