Motor Neuropathy Complete Antibody Panel

Test Code
90137


CPT Codes
82784 (x3), 83520 (x6), 86334, 86335 

Includes
Immunofixation, Serum
Immunoglobulins Panel, Serum
Ganglioside GM-1 Antibodies (IgG, IgM), EIA
Ganglioside GD1a Antibody (IgG), EIA
Ganglioside GD1a Antibody (IgM), EIA
Ganglioside Asialo-GM-1 Antibody (IgG), EIA
Ganglioside Asialo-GM-1 Antibody (IgM), EIA
Immunofixation (IFE), Urine


Preferred Specimen
5 mL serum and 25 mL random urine, no preservative collected in a plastic screw-cap container


Patient Preparation
Overnight fasting is preferred

Minimum Volume
2 mL serum • 10 mL random urine


Other Acceptable Specimens
Serum and 24-hour urine (no preservative)


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Serum
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 30 days

Urine
Room temperature: 5 days
Refrigerated: 7 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
See individual assays


Methodology
Immunofixation • Immunoturbidometry • Immunoassay (IA)

Setup Schedule
See individual assays


Clinical Significance
The panel includes ganglioside antibodies associated with motor neuropathies. Many of the anti-ganglioside antibodies associated with chronic immune neuropathies are monoclonal IgM antibodies. An evaluation for monoclonal gammopathy should be performed in this setting.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.