Lipase

Test Code
606


CPT Codes
83690

Preferred Specimen
1 mL serum


Patient Preparation
The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for...cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.

Minimum Volume
0.5 mL


Instructions
Note: N-acetyl-p-benzoquinone imine (NAPQI) (metabolite of acetaminophen) will generate erroneously low results in samples for patients that have taken toxic doses of acetaminophen.


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 8 days
Refrigerated: 8 days
Frozen: 31 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly icteric


Methodology
Spectrophotometry (SP)

Setup Schedule

Set up: Mon-Fri; Report available: 3-6 days



Clinical Significance
Confirmatory evidence for diagnosis of pancreatitis.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.