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Lactic Acid, CSF
Test Code1659
CPT Codes
83605
Preferred Specimen
1 mL CSF in a sterile, plastic screw-cap container
Minimum Volume
0.5 mL
Instructions
If specimen is not clear or contains blood, centrifuge and separate supernatant fluid before freezing.
The assay manufacturer, Roche, notes that N-acetylcysteine, when administered in high concentrations (such as for treatment of acetaminophen overdose), can interfere with their assay for lactate (lactic acid), leading to falsely low results.
Transport Temperature
Frozen
Specimen Stability
Room temperature: 3 hours
Refrigerated: 24 hours
Frozen: 90 days
Refrigerated: 24 hours
Frozen: 90 days
Methodology
Spectrophotometric
Setup Schedule
Set up: Sun-Fri; Report Available: 3-5 days
Clinical Significance
Lactic Acid levels in CSF normally parallel blood levels. Increased CSF Lactic Acid levels occur in trauma, seizure, brain abscess, Multiple Sclerosis, and bacterial meningitis.
