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Lactate Dehydrogenase (LD)
Test Code593
CPT Codes
83615
Preferred Specimen
2 mL serum collected in an SST® (serum separator tube)
Minimum Volume
0.5 mL
Other Acceptable Specimens
Plasma collected in a: sodium or lithium heparin (green-top), or EDTA (lavender-top), or EDTA (royal blue-top), or EDTA PPT potassium (white-top) tube
Instructions
Hemolyzed specimens are not acceptable
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 48 hours
Frozen: Unacceptable
Refrigerated: 48 hours
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis
Methodology
Spectrophotometry (SP)
Setup Schedule
A.M. Sets up 5 days a week.
Clinical Significance
Elevations in serum lactate dehydrogenase occur from myocardial infarction, liver disease, pernicious and megaloblastic anemia, pulmonary emboli, malignancies, and muscular dystrophy. Since lactic dehydrogenase is present in many body tissues, it's diagnosis usefulness is limited. Tissue specificity may be enhanced by isoenzyme analysis.
