A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
JC Polyoma Virus DNA, Qualitative, Real-Time PCR, CSF
Test Code16441
CPT Codes
87798
Preferred Specimen
0.7 mL CSF collected in a sterile leak-proof container
Minimum Volume
0.3 mL
Transport Temperature
Frozen
Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Methodology
Real-Time Polymerase Chain Reaction
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
A.M.
Report Available
Reports in 1 day
Clinical Significance
JC Polyoma Virus (JCV) is the cause of progressive multi- focal leukoencephalopathy (PML), a demyelinating neurologic disease of immunosuppressed patients. This test detects JC polyoma virus DNA in CSF. Detection of the virus in specimens from AIDS and other severely immune compromised patients may indicate disease. Serum antibodies are not helpful in diagnosing PML as antibodies are common in the general population. JCV can also be detected in the urine of 3% of pregnant women, but is not associated with proven disease.