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Histoplasma Antibody, Complement Fixation, Serum
Test Code938
CPT Codes
86317 (x2)
Includes
Yeast Phase Antibody and Mycelial Phase Antibody
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Instructions
For CSF, use test code 5297- Histoplasma Antibody, Complement Fixation, CSF
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly icteric
Methodology
Complement Fixation (CF)
Setup Schedule
Set up: Tue-Sat; Report available: 2-5 days
Clinical Significance
This test is used for the diagnosis and prognosis of histoplasma infections. Titers ≥1:32 are highly suggestive of H. capsulatum infection. The CF test is more frequently positive with sera from chronic active pulmonary histoplasmosis than sera from primary active pulmonary disease.

