Gastrin, 5 Specimens

Test Code

CPT Codes
82941, 82938 (x4)

Preferred Specimen
1 ml frozen serum per specimen

Patient Preparation
Overnight fasting (12 hours).
The serum secretin test requires patients to be off of antacids and anticholinergic medications for 12 hours prior to the test. Proton pump inhibitors should not be discontinued because of concern of complications (acute bleeding and/or perforation if acid suppression is discontinued).

Minimum Volume
0.5 mL each specimen

Secretin Stimulation: The secretin used is a preparation from RepliGen ((GIH Stimulation). For this protocol, 0.4 mcg of secretin per kilogram of body weight is infused by intravenous bolus. Serum for gastrin is collected at -10 minutes and -1 minute before secretin injection, and +2 minutes, +5, +10, +15, +20, and +30 minutes after secretin stimulation. Label each tube with time of collection.

Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.

Transport Temperature

Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric • Received thawed


Setup Schedule
A.M. Sets up 3 days a week.

Report Available
Reports in 1 day.

Clinical Significance
For the diagnosis and monitoring of gastrin-secreting tumors, gastric ulcer, Zollinger-Ellison syndrome.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.