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Gastrin, 4 Specimens
Test Code6724
CPT Codes
82941, 82938 (x3)
Preferred Specimen
1 ml frozen serum per specimen
Patient Preparation
Overnight fasting (12 hours).
The serum secretin test requires patients to be off of antacids and anticholinergic medications for 12 hours prior to the test. Proton pump inhibitors should not be discontinued because of concern of complications (acute bleeding and/or perforation if acid suppression is discontinued).
Minimum Volume
0.5 mL each specimen
Instructions
Secretin Stimulation: The secretin used is a preparation from RepliGen ((GIH Stimulation). For this protocol, 0.4 mcg of secretin per kilogram of body weight is infused by intravenous bolus. Serum for gastrin is collected at -10 minutes and -1 minute before secretin injection, and +2 minutes, +5, +10, +15, +20, and +30 minutes after secretin stimulation. Label each tube with time of collection.
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 28 days
Refrigerated: Unacceptable
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric • Received thawed
Methodology
Immunoassay
Setup Schedule
A.M. Sets up 3 days a week.
Report Available
Reports in 1 day.
Clinical Significance
For the diagnosis and monitoring of gastrin-secreting tumors, gastric ulcer, Zollinger-Ellison syndrome.