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Fungitell® (1-3)-ß-D-Glucan Assay

Test Code
16283


CPT Codes
87449

Preferred Specimen
1 mL serum


Minimum Volume
0.5 mL


Instructions
Draw blood in plain red-top tube or Serum Separator Tube (SST®), spin down, then aliquot off into a cryogenic vial (DNAse, RNAse, pyrogen-free). Glucan-free tubes are acceptable.


Transport Container
Cryogenic vial


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: Unacceptable
Refrigerated: 5 days
Frozen: 14 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia • Icteric • Turbid serum • Specimens other than serum • Glass tubes


Methodology
Protease Zymogen-based Colorimetric

Setup Schedule

Set up: Daily; Report available: 1-2 days



Clinical Significance
Invasive Fungal Infections (IFI) are increasing, especially among immunocompromised patients. Most pathogenic fungi have (1-3)-beta-D-glucan in their cell walls and minute quantities are sloughed into the bloodstream and appear in the serum in cases of IFI. Monitoring serum (1-3)-beta-D-glucan for evidence of elevated and rising levels provides a convenient surrogate marker for IFI.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.