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FISH, Oligodendroglioma, 1p/19q
Test Code16115X
CPT Codes
88365, 88364
Preferred Specimen
Formalin fixed paraffin-embedded tissue block
Instructions
Submit Formalin-fixed, paraffin-embedded human oligodendroglioma tissue.
Specimen viability decreases during transit. Send specimen to testing lab for viability determination.
Specimen viability decreases during transit. Send specimen to testing lab for viability determination.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: See Instructions
Refrigerated: See Instructions
Frozen: Unacceptable
Refrigerated: See Instructions
Frozen: Unacceptable
Methodology
Fluorescence in situ Hybridization (FISH)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Sets up 7 days a week.
Clinical Significance
Oligodendroglioma tumors exhibit simultaneous deletions of 1p and 19q in two thirds of cases. These deletions have been associated with a favorable response to chemotherapy with long survival.