FISH, IGH/CCND1, t(11;14)

Test Code

17346

CPT Codes
88275, 88271 (x2)

Preferred Specimen

5 mL whole blood or 3 mL bone marrow collected in a sodium heparin (green-top) tube
5x5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution
Formalin-fixed paraffin-embedded tissue

Minimum Volume

1 mL

Other Acceptable Specimens

Whole blood or bone marrow collected in: Sodium heparin (royal blue-top) tube or sodium heparin lead-free (tan-top) tube

Instructions

3-5 mL whole blood or 1-3 mL bone marrow collected in a sodium heparin tube, 5x5 mm Fresh tissue in sterile container, Formalin Fixed Paraffin Embedded Tissue.

Transport Temperature

Room temeprature

Specimen Stability

Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.

Methodology
Fluorescence in situ Hybridization (FISH)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Daily; Report Available: 5-7 days

Clinical Significance

This test is performed to detect the IGH-CCND1 fusion, translocation t(11;14) by FISH (fluorescence in situ hybridization). This assay is useful for diagnosis of mantle cell lymphoma and, risk assessment for plasma cell myeloma.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.