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FISH, MALT Lymphoma, MALT1, 18q21 Rearrangement
Test Code40053
CPT Codes
88271 (x2), 88275
Preferred Specimen
5 mL whole blood collected in a sodium heparin (green-top) tube or
3 mL bone marrow collected in a sodium heparin (green-top) tube
3 mL bone marrow collected in a sodium heparin (green-top) tube
Minimum Volume
1 mL
Other Acceptable Specimens
Formalin-fixed, paraffin-embedded tissue • 5x5 mm lymph node tissue or lymph node collected in a sterile container
Instructions
For bone marrow (1-3 mL) or whole blood (3-5 mL) use green top (sodium heparin) tube. For lymph node biopsy 5x5 mm in a sterile container in Hank's Ringer's solution or culture medium with antibiotics. Transportation medium available upon request.
Formalin fixed paraffin embedded tissue. Specimen viability decreases during transit.
Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Formalin fixed paraffin embedded tissue. Specimen viability decreases during transit.
Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Transport Temperature
Room temperature
Specimen Stability
See Collection Instructions
Methodology
Fluorescence in situ Hybridization (FISH)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Daily; Report Available: 5-7 days
Clinical Significance
Prognostic investigation of mucosa-associated lymphoid tissue (MALT) lymphoma.