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FISH, Ewing/PNET, EWSR1, 22q12 Rearrangements
Test Code16112
CPT Codes
88271 (x2), 88275
Preferred Specimen
Fresh-fixed, paraffin-embedded specimen or
3 mL bone marrow collected in a sodium heparin (green-top) tube or
5 x 5 mm tissue biopsy collected in transport medium
3 mL bone marrow collected in a sodium heparin (green-top) tube or
5 x 5 mm tissue biopsy collected in transport medium
Minimum Volume
1 mL
Instructions
Transport Temperature
Room temperature
Specimen Stability
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. **Do not reject**
Methodology
Fluorescence in situ Hybridization (FISH)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Sets up 7 days a week.
Clinical Significance
A FISH Ewing sarcoma assay by using the LSI (R) EWSR1 (22q12) Dual Color, Break Apart Rearrangement Probe (Vysis) to identify chromosomal rearrangements of the EWSR1 gene region.