A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
FISH, Burkitt's/NHL/ALL, IGH/MYC, t(8;14)
Test Code17352
CPT Codes
88275, 88271 (x3)
Preferred Specimen
5 mL whole blood or 3 mL bone marrow collected in sodium heparin (green-top), sodium heparin (royal blue-top) or sodium heparin lead-free (tan-top) tube, or
5x5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution, or
Formalin-fixed paraffin-embedded tissue
5x5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution, or
Formalin-fixed paraffin-embedded tissue
Minimum Volume
1 mL
Instructions
Submit 3-5 mL whole blood or 3 mL bone marrow collected in sodium heparin tube, 5x5 mm Fresh tissue in sterile container, Formalin Fixed Paraffin Embedded Tissue.
Transport Temperature
Room temperature
Specimen Stability
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not Reject.
Methodology
Fluorescence in situ Hybridization (FISH)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Daily; Report available: 5-7 days
Clinical Significance
The translocation T(8;14)(Q24.1;Q32) is assayed by FISH with probes from the regions C-MYC (8Q24.1) and IGH (14Q32). This assay is useful to diagnose Burkitt's type lymphoma and some cases of Acute Lymphoblastic Leukemia.