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Euglobulin Clot Lysis Time
Test Code462
CPT Codes
85360
Preferred Specimen
2 mL frozen plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
1 mL
Instructions
Specimen collection container is blue-top (3.2% sodium citrate) tube. To avoid release of plasminogen activator, do not massage vein vigorously, pump fist excessively or leave tourniquet in place for a prolonged period. Centrifuge within 30 minutes after collection to get platelet-poor plasma and freeze on dry ice.
Ship specimens frozen on dry ice. Keep samples in a -60° to -80° C freezer if they cannot be shipped promptly. Prohibit exercise prior to drawing sample.
Ship specimens frozen on dry ice. Keep samples in a -60° to -80° C freezer if they cannot be shipped promptly. Prohibit exercise prior to drawing sample.
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 4 hours
Frozen: 21 days
Refrigerated: 4 hours
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia • Icteric • Received room temperature • Received refrigerated
Methodology
Clot Dissolution
Setup Schedule
Sets up 1 day a week.
Report Available
Reports in 3 days.
Clinical Significance
Euglobulin clot lysis time (ECLT) provides an overall assessment of the fibrinolysis system by measuring the time for an in vitro clot to dissolve in the absence of the normal plasmin inhibitors. ECLT is useful in assessing the fibrinolytic system and monitoring patients on urokinase or streptokinase fibrinolytic therapy.
