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Echovirus Antibodies, Serum
Test Code35139
CPT Codes
86658 (x5)
Includes
Echovirus serotypes 4, 7, 9, 11, and 30
Preferred Specimen
2 mL serum
Minimum Volume
1 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Methodology
Complement Fixation (CF)
Setup Schedule
Set up: Tue-Sat; Report available: 2-5 days
Clinical Significance
The current echovirus panel includes serotypes 4, 7, 9, 11, and 30. The echovirus serotypes used in this panel will vary depending upon current epidemiological data available from inhouse isolations CDC reports. Generally, the serotypes used are those most commonly associated with viral meningitis. Although there is cross-reactivity among the enteroviruses, most healthy people do not have detectable CF titers (>1:8). Therefore, detectable titers, especially those >1:32, should be considered diagnostic. Confirmed serodiagnosis is made by demonstration of a four-fold change in titers between acute and convalescent sera.