| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Collagen Cross-Linked N-Telopeptide (NTx), Urine
Test Code36167
CPT Codes
82523, 82570
Includes
Creatinine
Preferred Specimen
2 mL unpreserved urine collected from second morning void
Minimum Volume
1 mL
Other Acceptable Specimens
Unpreserved random urine • Unpreserved catheterized urine • Unpreserved first void clean catch urine
Instructions
Do not use preservatives. Acidified specimen is not acceptable.
Second morning void urine: Discard the first morning void. Collect the second morning void. Mix well.
Second morning void urine: Discard the first morning void. Collect the second morning void. Mix well.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 72 hours
Refrigerated: 5 days
Frozen: 30 days
Refrigerated: 5 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Acidified specimen • Preserved specimen
Methodology
Chemiluminescence (CL)
Setup Schedule
Set up: Mon, Wed, Fri; Report available: 3-6 days
Clinical Significance
NTx is useful to assess bone resorption in patients with metabolic bone disease. The test is also useful in monitoring therapy to slow or halt osteoporotic bone loss. A decline of 30% or more of NTx over a six-month period suggests effective therapy.
