A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Collagen Cross-Linked N-Telopeptide (NTx), 24-Hour Urine
Test Code36421
CPT Codes
82523, 82570
Includes
Creatinine
CPT code 81050 may be added at an additional charge for volume measurement
CPT code 81050 may be added at an additional charge for volume measurement
Preferred Specimen
2 mL of a 24-hour urine collection - no preservative
Minimum Volume
1 mL
Instructions
Do not include first morning specimen; collect all subsequent voidings. The last sample collected should be the first morning specimen voided the following morning at the same time as the previous morning's first voiding. Specify 24-hour total volume on container and test requisition.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 72 hours
Refrigerated: 5 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Acidified specimen • Preserved
specimen
specimen
Methodology
Chemiluminescence (CL)
Setup Schedule
Set up: Sun, Tues, Thurs; Report available: 1-4 days
Limitations
Collagen Cross-Linked N-Telopeptide is affected by diurnal variation.
Clinical Significance
NTx is useful to assess bone resorption in patients with metabolic bone disease and monitor therapy to slow or halt osteoporotic bone loss. A decline of 30% or more of NTx over a six-month period suggests effective therapy.