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CDX2, IHC with Interpretation
Test Code90153
CPT Codes
88342
Preferred Specimen
Formalin fixed paraffin embedded tissue in an IHC specimen transport kit
Other Acceptable Specimens
Unstained charged (+) slides collected in IHC specimen transport kit (x5)
Instructions
Please include surgical pathology report
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinite
Refrigerated: Indefinite
Frozen: Unacceptable
Refrigerated: Indefinite
Frozen: Unacceptable
Methodology
Immunohistochemistry
Setup Schedule
A.M. Sets up 5 days a week
Report Available
Reports in 2 to 3 days
Clinical Significance
CDX-2, a nuclear transcription factor that is expressed in colonic epithelium, is useful in distinguishing metastatic carcinoma of colorectal origin from other tumors. However, its expression may be lost in advanced colorectal tumors and is also expressed by some mucinous tumors of other sites.