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Calprotectin, Stool
Test Code16796
CPT Codes
83993
Preferred Specimen
3 grams solid stool collected in a Quest standard stool container without preservative or a clean, leak-proof plastic screw-cap container without preservative
Minimum Volume
0.3 g
Other Acceptable Specimens
Liquid or semi-liquid stool collected in a Quest standard stool container without preservative or a clean, leak-proof, plastic screw-cap container without preservative
Instructions
Quest standard stool container without preservative is available through Client Supply.
Room temperature stability: Stable for 6 days. However due to the sample type, it is not recommended to keep stool sample at room temperature.
Room temperature stability: Stable for 6 days. However due to the sample type, it is not recommended to keep stool sample at room temperature.
Transport Temperature
Frozen
Specimen Stability
Room temperature: 6 days
Refrigerated: 7 days
Frozen -20° C: 28 days
Frozen -70° C: 1 year
Refrigerated: 7 days
Frozen -20° C: 28 days
Frozen -70° C: 1 year
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Stool specimen collected in a container with fixative or preservative • Stool specimen collected during surgical procedure • Other specimen rather than raw stool sample
Methodology
Chemiluminescence (CL)
Setup Schedule
A.M.
Limitations
NSAIDs may cause elevated results.
Clinical Significance
Calprotectin is a non-specific marker of bowel inflammation. Subsequent to white blood cell migration into the intestine, this neutrophil protein may be detected in the stool. Thus, fecal calprotectin levels may assist in diagnosis of inflammatory bowel disease; Crohn's disease and ulcerative colitis and other disorders characterized by bowel inflammation. It can also be used as an aid in the differentiation of IBD from irritable bowel syndrome.
