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CAH Panel 9 (3Beta-Hydroxysteroid Dehydrogenase Deficiency)
Test Code15280
CPT Codes
84143, 83498, 82626, 82157, 82533
Includes
17-Hydroxyprogesterone
Androstenedione
17-Hydroxypregnenolone
DHEA, (Dehydroepiandrosterone), Unconjugated
Cortisol, Total, LC/MS
Androstenedione
17-Hydroxypregnenolone
DHEA, (Dehydroepiandrosterone), Unconjugated
Cortisol, Total, LC/MS
Preferred Specimen
3 mL serum collected in a red-top tube (no gel)
Minimum Volume
1 mL
Instructions
An early morning specimen is preferred. Specify time of day specimen was collected. Specify age and sex on test requisition.
Transport Temperature
Frozen
Specimen Stability
Room temperature: 6 hours
Refrigerated: 72 hours
Frozen: 28 days
Refrigerated: 72 hours
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum Separator Tubes (SST®) • Plasma • Gross hemolysis • Received room temperature
Methodology
See individual tests
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
See individual assays
Clinical Significance
Total cortisol concentrations are decreased in Addison's disease and increased in Cushing's disease and in other conditions of glucocorticoid excess.