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BK Virus DNA, Qualitative, Real-Time PCR, Plasma
Test Code11351X
CPT Codes
87798
Includes
For CSF: Please use 18889 BK Virus DNA, Qualitative Real-Time PCR, CSF.
For Urine: Please use (16553X) [16553] BK Virus DNA, Qualitative Real-Time PCR, Urine.
For Urine: Please use (16553X) [16553] BK Virus DNA, Qualitative Real-Time PCR, Urine.
Preferred Specimen
0.7 mL plasma collected in an EDTA (lavender-top), or ACD (yellow-top) tube
Minimum Volume
0.3 mL
Other Acceptable Specimens
Serum • Whole blood collected in: EDTA (lavender-top), or ACD (yellow-top) tube
Transport Temperature
Plasma/Serum: Frozen
Whole blood: Refrigerated (cold packs)
Specimen Stability
Plasma and serum
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Whole blood
Room temperature: 48 hours
Refrigerated: 8 days
Frozen: Unacceptable
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Whole blood
Room temperature: 48 hours
Refrigerated: 8 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Sodium heparin (green-top) tube • Lithium heparin (green-top) tube
Methodology
Real-Time Polymerase Chain Reaction
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Sets up 7 days a week.
Clinical Significance
This test is used to determine the presence of BK Virus DNA in patients' specimens. Detection of the virus in these specimens may be indicative of an active infection, as pcr detects the presence of the virus, and not the host's reaction to the virus. Polyomavirus BK DNA detection in plasma, serum and whole blood is associated with an increased risk of graft rejection in renal transplant recipients.