Biotinidase

Test Code

70132X

CPT Codes
82261

Preferred Specimen

2 mL serum

Minimum Volume

1 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube, lithium heparin (green-top) tube or sodium heparin (green-top) tube

Instructions

Separate serum or plasma within one hour of collection and store at minimum -20° C or below. Use dry ice for shipment.

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Received room temperature • Received refrigerated

Methodology
Colorimetric (C) • Enzymatic

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

P.M. Sets up 2 days a week.

Clinical Significance

Detect biotinidase deficiency. Children born with biotinidase deficiency develop mental retardation; it is a very treatable disorder once diagnosed.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.