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Amylase Isoenzymes with Reflex to Macroamylase
Test Code36187
CPT Codes
82150 (x2)
Includes
Amylase, Pancreatic Isoenzyme, Salivary Isoenzymes (calculated)
If Amylase Isoenzymes are >115 U/L, then Macroamylase will be performed at an additional charge (CPT code(s): 82150).
If Amylase Isoenzymes are >115 U/L, then Macroamylase will be performed at an additional charge (CPT code(s): 82150).
Preferred Specimen
2 mL serum
Minimum Volume
1 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 21 days
Refrigerated: 7 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis
Methodology
Enzymatic
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
A.M. Sets up 2 days a week.
Limitations
Oxalate, citrate, and lipemic sera can decrease results.
Clinical Significance
Amylase is produced primarily in the pancreas and salivary glands. Isoenzymes may be used to determine the source of an elevated amylase concentration. Macroamylase is a laboratory and not a clinical entity. Amylase can complex with immunoglobulins or other high molecular weight proteins and serum amylase will appear falsely elevated. No clinical symptoms are associated with macroamylasemia.
