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Alpha-2-Macroglobulin (228X)
Test Code18358P
CPT Codes
83883
Preferred Specimen
1 mL serum
Patient Preparation
Overnight fasting is preferred
Minimum Volume
0.5 mL
Instructions
Avoid hemolysis
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 90 days
Refrigerated: 7 days
Frozen: 90 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature
Methodology
Fixed Rate Time Nephelometry
Setup Schedule
A.M.
Clinical Significance
Alpha-2-Macroglobulin is produced in the liver. Increased concentrations are associated with patients with some chronic liver diseases, nephrotic syndrome, and diabetes. Decreased concentrations are associated with patients with pancreatitis, rheumatoid arthritis, and multiple myeloma.
