| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Alpha-1-Antitrypsin Quantitation
Test Code235
CPT Codes
82103
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Instructions
Allow blood to clot in the original closed container at room temperature (usually 20 to 30 minutes). After clot has formed, centrifuge blood 10 minutes at a relative centrifugal force (CRF) of 850 to 1000 g in the stoppered container.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 90 days
Refrigerated: 7 days
Frozen: 90 days
Methodology
Immunoturbidimetric Assay
Setup Schedule
Set up: Tues, Thurs, Sat; Report available: 2-4 days
Clinical Significance
Alpha-1-Antitrypsin level may be increased in normal pregnancy and in several diseases including chronic pulmonary disease; hereditary angioedema; renal, gastric, liver and pancreatic diseases; diabetes; carcinomas and rheumatoid diseases. Alpha-1-Antitrypsin may be decreased in emphysema, hepatic cirrhosis, respiratory distress syndrome of the newborn, nephrosis, malnutrition and cachexia. If a deficiency is present, aat phenotyping may be considered to confirm heterozygous versus homozygous deficiencies.
