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Alkaline Phosphatase, Bone Specific
Test Code29498
CPT Codes
84075
Preferred Specimen
1 mL serum
Minimum Volume
0.3 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 21 days
Refrigerated: 7 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Non-serum samples • Grossly icteric
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report available: 1-2 days
Clinical Significance
The bone-specific alkaline phosphatase (BSAP) assay provides a general index of bone formation and a specific index of total osteoblast activity. BSAP and osteocalcin are the most effective markers of bone formation and are particularly useful for monitoring bone formation therapies and antiresorptive therapies.
