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Alkaline Phosphatase
Test Code234
CPT Codes
84075
Preferred Specimen
1 mL serum collected in a Serum Separator Tube (SST®)
Minimum Volume
0.5 mL
Other Acceptable Specimens
Plasma collected in a sodium heparin (green-top) or lithium heparin (green-top) tube
Instructions
Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
Transport Temperature
Room temperature
Specimen Stability
Serum and plasma
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Anticoagulants other than heparin
Methodology
Spectrophotometry (SP)
Setup Schedule
A.M. Sets up 6 days a week.
Clinical Significance
Serum alkaline phosphatase levels are of interest in the diagnosis of hepatobiliary disorders and bone disease associated with increased osteoblastic activity. Moderate elevations of alkaline phosphatase may be seen in several conditions that do not involve the liver or bone. Among these are Hodgkin's disease, congestive heart failure, ulcerative colitis, regional enteritis, and intra-abdominal bacterial infections. Elevations are also observed during the third trimester of pregnancy.
