A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Osteocalcin, N MID
Test Code60942YCTC
CPT Codes
83937
Preferred Specimen
1 mL serum
Patient Preparation
Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Minimum Volume
0.5 mL
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 24 hours
Frozen: 21 days
Refrigerated: 24 hours
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Heat inactivated specimens • Specimens stabilized with
azide • Patient administered with biotin within 8 hours
azide • Patient administered with biotin within 8 hours
Methodology
Electrochemiluminescence Immunoassay (ECLIA)
Setup Schedule
A.M. Sets up 3 days a week.
Clinical Significance
Osteocalcin, the most abundant non-collagen protein in bone matrix, is a bone-specific, calcium binding protein. Serum osteocalcin levels are related to the rate of bone turnover in various disorders of bone metabolism, e.g., osteoporosis, primary and secondary hyperparathyroidism, and Paget's disease.