Metanephrines, VMA, Catecholamines, 24-Hour Urine (Client 8767)

Test Code

P9105BL

CPT Codes
82384, 82570, 83835, 84585<br /> **Restricted use** This code is available for Client 8767 and 58240 ONLY

Preferred Specimen

25 mL 24-hour urine collected with 6N HCL

Patient Preparation
It is preferable for the patient to be off medications for three days prior to collection.
Patient should avoid tobacco, tea, coffee, for three days prior to specimen collection. Common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Medications which are alpha agonists (Aldomet), alpha blockers (Dibenzyline) should be avoided 18-24 hours prior to specimen collection.

Minimum Volume

11.5 mL

Other Acceptable Specimens

Urine with no preservative

Instructions

Collect 24-hour urine with 25 mL of 6N HCl to maintain a pH below 3. Urine without preservative is acceptable if pH is below 6 and the sample is shipped frozen. Record 24-hour urine volume on test request form and urine vial.

Transport Temperature

Room temperature

Specimen Stability

Preserved Urine
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 49 days

Unpreserved Urine
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Urine collected with Boric acid • Preserved urine received refrigerated with pH >3 • unpreserved urine received frozen with pH >6

Methodology
High Performance Liquid Chromatography (HPLC) • Electrochemical Detection • Kinetic Alkaline Picrate • Liquid Chromatography Tandem Mass Spectrometry (LCMSMS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

See individual assays

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.