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Celiac Disease Diagnostic Panel
Test Code15681X
CPT Codes
82784, 86364 (x2), 86258 (x2)
Includes
Tissue Transglutaminase (tTG) Antibodies (IgG, IgA)
Gliadin (Deamidated) Antibody (IgG, IgA)
IgA (Immunoglobulin A)
Gliadin (Deamidated) Antibody (IgG, IgA)
IgA (Immunoglobulin A)
Preferred Specimen
3 mL serum
Minimum Volume
1.5 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunoassay (IA) • Immunoturbidimetric Assay
Setup Schedule
Set up: Mon-Sat; Report available: 2-4 days
Clinical Significance
Celiac disease is characterized by the presence of Transglutaminase, Gliadin, and Reticulin Antibodies. Such patients display a hypersensitivity to gluten (wheat) in their diet. The antibody is undetectable when patients with hypersensitivity are placed on gluten-free diets. Antibody IgA is more specific and IgG is more sensitive to Celiac disease.
