Entrapment Neuropathy Evaluation

Test Code
93398


CPT Codes
<br><strong>Restricted Use. This code is available for Clients 51613, 58536 57452 54279 and 4074 ONLY.</strong>

Physician Attestation of Informed Consent
This germline genetic test requires physician attestation that patient consent has been received if ordering medical facility is located in AK, DE, FL, GA, IA, MA, MN, NV, NJ, NY, OR, SD or VT or test is performed in MA.


Preferred Specimen
8 mL whole blood collected in two EDTA (lavender-top) tubes
Pediatric (0-3 Years): 2 mL


Minimum Volume
6 mL • Pediatric: 1 mL


Instructions
Please label each specimen with two forms of patient identification. These forms of identification must also appear on the requisition form.

Note: Higher blood volumes ensure adequate DNA quantity, which varies with WBC, specimen condition, and need for confirmatory testing. Patients, 0-3 years may have higher WBC, yielding more DNA per mL of blood.


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 10 days
Refrigerated: 10 days
Frozen: Unacceptable


Methodology
Sanger Sequencing • Multiplex Ligation-dependent Probe Amplification (MLPA) • Next Generation Sequencing

Setup Schedule
Report available: 14-28 days


Clinical Significance
Detects duplications, deletions, and sequence variants in the PMP22 gene and sequence variants in Transthyretin gene
Typical Presentation: Weakness and pain with motor or sensory disturbances indicative of a focal or multifocal compression neuropathy




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.