Cholinesterase, Serum (California Clients)

Test Code

90371

CPT Codes
82480<br>**This test is for California patients. For non-California patient testing, use 37965**

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Instructions

Centrifuge and transfer serum specimens to clean, plastic, screw-capped vial(s)

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold-packs)

Specimen Stability

Room temperature: 21 days
Refrigerated: 21 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis

Methodology
Kinetic Spectrophotometric (KS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics Nichols Institute. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

A.M. Sets up 5 days a week.

Clinical Significance

Approximately 1 in every 2500 individuals has inherited defective or deficiency of the enzyme (pseudocholinesterase) that metabolizes succinylcholine (an anesthetic agent). With "normal" dosage, these individuals have prolonged apnea. Such individuals are responsive at much smaller concentrations of this anesthetic agent than the general population. Low concentrations of Pseudocholinesterase are observed in individuals exposed to organophosphorous insecticides and patients with hepatic dysfunction.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.