Cortisol Response to ACTH Stimulation, Serum (Client 8807)

Test Code

14CS

CPT Codes
82533 (x3)<br>*RESTRICTED* This code is available for clients 8807 and 6374 only. <br><br data-cke-filler="true">

Preferred Specimen

1 mL serum collected in each of three separate red-top tubes (no gel)

Minimum Volume

0.2 mL in each of three separate tubes

Other Acceptable Specimens

Plasma collected in EDTA (lavender-top) tube

Instructions

For each timed specimen submitted, each tube must be clearly marked with time drawn. Submit all tubes with one test request form.

Draw morning baseline specimen. Administer 250 ug Cortrosyn. Draw additional specimens at 30 and 60 minutes.

Note: Cortrosyn (cosyntropin) not supplied by the laboratory. This test cannot be collected at a Patient Service Center.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 14 days
Refrigerated: 21 days
Frozen: 1 year

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Serum separator tubes (SST) • Gross hemolysis

Methodology
Chromatography/Mass Spectrometry

Setup Schedule

Night Sets up 6 days a week.

Report Available

Reports in 1 day.

Clinical Significance

The cortisol response to infusion of synthetic ACTH is useful in diagnosing patients with adrenal insufficiency (Addison's disease).

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.