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Fungitell® 1-3-B-D-Glucan with reflex to Fungitell 1-3B-D-Gluc,End (Client SMCSR)
Test Code10092CP
CPT Codes
87449
Preferred Specimen
2 mL serum
Minimum Volume
1 mL
Instructions
Draw blood in plain red-top tube or serum separator tube, spin down, then aliquot off into a cryogenic vial (DNAse, RNAse, pyrogenfree). Glucan free tubes are acceptable.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 5 days
Frozen: 14 days
Refrigerated: 5 days
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia • Icteric • Turbin serum • Specimens other than serum • Glass tubes
Methodology
Protease Zymogen-Based Colorimetric
Setup Schedule
Sets up 7 days a week.
Report Available
Reports in 1 to 2 days.
Clinical Significance
Invasive fungal infections (IFI) are increasing, especially among immunocompromised patients. Most pathogenic fungi have (1->3)-beta-D-glucan in their cell walls and minute quantities are sloughed into the bloodstream and appear in the serum in cases of IFI. Monitoring serum (1->3)-beta-D-glucan for evidence of elevated and rising levels provides a convenient surrogate marker for IFI.