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Epidermal Growth Factor Receptor (EGFR) Mutation with Reflexes
Test Code10017CP
CPT Codes
81235<br /> *** RESTRICTED USE *** This code is available to KAISER ONLY<br />
Includes
If EGFR Mutation Analysis is Negative, then reflex to 10017-2 ALK FISH NSCLC. If 10017-2 ALK FISH NSCLC is Negative, then reflex to 10017-3 ROS1 FISH. If 10017-3 ROS1 FISH is Negative, then reflex to 10017-4 BRAF Mutation Analysis. If 10017-4 BRAF Mutation Analysis is Negative, then reflex to 10017-5 PD-L1.
** All Reflex testing will be performed at additional charges.**
** All Reflex testing will be performed at additional charges.**
Preferred Specimen
Formalin fixed paraffin embedded tissue block
Instructions
See individual assays
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 years
Refrigerated: 5 years
Frozen: Unacceptable
Refrigerated: 5 years
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Frozen or thawed tissue • Fresh tissue • Non-fixed tissue • Cytology cell block • Decalcified specimens • Fixatives other than formalin • Baked or melted slides • Previously stained than formalin • Previously stained slides • Cytospins • Lung cancer specimens: (primary or metastatic) are the only acceptable tissue type • Other tissue types submitted will be rejected
Methodology
See individual assay.
Setup Schedule
See individual assays
Clinical Significance
See individual assays
