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Rickettsia (Typhus Fever) Antibodies (IgG, IgM) with Reflex to Titers
Test Code37503
CPT Codes
86757 (x2)
Includes
If R. typhi IgG is Detected, then R. typhi IgG Titer will be performed at an additional charge (CPT code(s): 86757).
If R. typhi IgM is Detected, then R. typhi IgM Titer will be performed at an additional charge (CPT code(s): 86757).
If R. typhi IgM is Detected, then R. typhi IgM Titer will be performed at an additional charge (CPT code(s): 86757).
Preferred Specimen
1 mL serum
Minimum Volume
0.2 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 day
Refrigerated: 14 days
Frozen: 30 day
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunofluorescent Assay (IFA)
Setup Schedule
Sets up 5 days a week.
Limitations
Even after infection has been treated, positive results may persist. False-positive reactions may occur during pregnancy.
Clinical Significance
Antigen specific IgG and IgM titers allow rapid diagnosis of infection by one or more of the typhus fever group of rickettsial agents. This group includes Rickettsia typhi (endemic or murine typhus) R. prowazeki (epidemic typhus), and Brill-Zinsser disease caused by reactivation of latent R. prowazeki.
