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Trichinella IgG Antibody, ELISA (34321X)
Test Code65631P
CPT Codes
86784
Preferred Specimen
1 mL serum
Minimum Volume
0.1 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Methodology
Enzyme Linked Immunosorbent Immunoassay (ELISA)
Setup Schedule
Set up: Wed; Report available: 1-7 days
Limitations
Antibody may remain detectable for two to three years following infection and treatment.
Clinical Significance
The ELISA technique for the detection of trichinella IgG antibody offers significant improvements in sensitivity compared to the widely-used Bentonite Flocculation (BF) and Latex Agglutination (LA) tests. An excretory-secretory antigen is employed to reduce nonspecific reactivity; however, crossreactivity with other parasitic antigens (e. g., strongyloides, filaria, malaria) may occur. Such crossreactivity is usually associated with results in the equivocal range. The trichinella antibody ELISA must be considered a screening test for trichinella exposure. The diagnosis of trichinosis requires a compatible patient history and supporting pathologic findings.