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JC Virus DNA, Ultrasensitive, Quantitative, Real-Time PCR, CSF
Test Code18939
CPT Codes
87799
Preferred Specimen
1.2 mL CSF collected in a sterile leak-proof container
Minimum Volume
0.6 mL
Transport Temperature
Frozen
Specimen Stability
Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Methodology
Real-Time Polymerase Chain Reaction (PCR)
FDA Status
This test was developed and its performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.
Setup Schedule
Set up: Mon-Sat; Report available: 1-3 days
Clinical Significance
JC polyoma virus (JCV) is the cause of progressive multifocal leukoencephalopathy (PML), a demyelinating neurologic disease of immunocompromised patients and patients on certain medications. This test detects and quantifies JCV in cerebrospinal fluid (CSF). Detection of the virus in CSF may indicate infection. This is a quantitative molecular test with a linear range of 50-10,000,000 IU/mL.
