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Arbovirus Antibody Panel (IgG, IgM), IFA, CSF
Test Code3621X
CPT Codes
86651 (x2), 86652 (x2), 86653 (x2), 86654 (x2)
Includes
California Encephalitis (IgG, IgM), Eastern Equine Encephalitis (IgG, IgM), St. Louis Encephalitis (IgG, IgM), Western Equine Encephalitis (IgG, IgM)
Preferred Specimen
1 mL CSF in a sterile screw-cap container
Minimum Volume
0.5 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Methodology
Immunofluorescence Assay (IFA)
Setup Schedule
Sets up 5 days a week.
Report Available
Reports in 2 to 6 days.
Limitations
False-positive results may be produced if the patient has been immunized against yellow fever or if the patient has had previous infections that produce similar, cross-reacting antibodies.
Clinical Significance
Arboviruses are classically defined as viruses that can be transmitted to humans by an arthropod vector. Arboviral diseases of humans may present with four manifestations: fever, encephalitis, hemorrhagic fever and polyarthritis. Fever is the most common sign and is usually benign, mild and undifferentiated, lasting 3-7 days. This panel includes of the following arboviruses that infect the central nervous system: St. Louis encephalitis, California encephalitis and Eastern and Western Equine encephalitis.
