SARS-CoV-2 Antibodies (IgG Nucleocapsid, IgM Spike), Qualitative

Test Code

31672

CPT Codes
86769<br><strong>To meet regulatory reporting requirements for COVID-19 testing, the patient's address, phone number and other demographic details are required for this order.</strong>

Preferred Specimen

1 mL serum

Minimum Volume

1 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Grossly icteric • Frozen serum separator tube (SST)

Methodology
Immunoassay (IA)

Setup Schedule

Set up: Daily; Report available: 1-2 days

Report Available

Reports in 1 to 2 days.

Clinical Significance

Detection of IgG and IgM antibodies may indicate exposure to SARS-CoV-2 (COVID-19). IgM antibodies to SARS-CoV-2 are generally detectable in blood several days after initial infection, with IgG antibodies typically reaching detectable levels simultaneously or 1-2 days later. Separate results will be provided for IgM and IgG. A positive antibody result may suggest an immune response to a primary infection with SARS-CoV-2, but the relationship between positivity and immunity to SARS-CoV-2 has not yet been firmly established. Antibody tests have not been shown to definitively diagnose or exclude SARS-CoV-2 infection. Diagnosis of COVID-19 is made by detection of SARS-CoV-2 RNA by molecular testing methods, consistent with a patient's clinical findings.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.