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Drug Monitoring, Panel 5, with Confirmation, Urine
Test Code39425
CPT Codes
80307
Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Initial screen of Amphetamines, Barbiturates, Benzodiazepines, Marijuana Metabolite, Cocaine Metabolite, Methadone, Opiates, Oxycodone drug classes. Specimen validity consisting of Creatinine, Oxidant, and pH testing.
If screen of drug class is positive, a confirmation of the drug class will be performed at an additional charge (CPT code(s): dependent upon the confirmed drug class).
Confirmation includes the following analytes within their associated drug class:
Amphetamines: Amphetamine, Methamphetamine
Barbiturates: Amobarbital, Butalbital, Pentobarbital, Phenobarbital, Secobarbital
Benzodiazepines: Alphahydroxyalprazolam, Alphahydroxymidazolam, Alphahydroxytriazolam, Aminoclonazepam, Hydroxyethylflurazepam, Lorazepam, Nordiazepam, Oxazepam, Temazepam
Marijuana Metabolite: Marijuana Metabolite
Cocaine Metabolite: Benzoylecgonine
Methadone Metabolite: EDDP, Methadone
Opiates: Codeine, Hydrocodone, Hydromorphone, Morphine, Norhydrocodone
Oxycodone: Noroxycodone, Oxycodone, Oxymorphone
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
.
Initial screen of Amphetamines, Barbiturates, Benzodiazepines, Marijuana Metabolite, Cocaine Metabolite, Methadone, Opiates, Oxycodone drug classes. Specimen validity consisting of Creatinine, Oxidant, and pH testing.
If screen of drug class is positive, a confirmation of the drug class will be performed at an additional charge (CPT code(s): dependent upon the confirmed drug class).
Confirmation includes the following analytes within their associated drug class:
Amphetamines: Amphetamine, Methamphetamine
Barbiturates: Amobarbital, Butalbital, Pentobarbital, Phenobarbital, Secobarbital
Benzodiazepines: Alphahydroxyalprazolam, Alphahydroxymidazolam, Alphahydroxytriazolam, Aminoclonazepam, Hydroxyethylflurazepam, Lorazepam, Nordiazepam, Oxazepam, Temazepam
Marijuana Metabolite: Marijuana Metabolite
Cocaine Metabolite: Benzoylecgonine
Methadone Metabolite: EDDP, Methadone
Opiates: Codeine, Hydrocodone, Hydromorphone, Morphine, Norhydrocodone
Oxycodone: Noroxycodone, Oxycodone, Oxymorphone
Preferred Specimen
30 mL urine in a clinical drug test transport vial
Minimum Volume
7 mL
Other Acceptable Specimens
Urine collected in urine collection container
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Preserved samples
Methodology
Screen: Immunoassay (IA) • Confirmation: Mass Spectrometry (MS)
Setup Schedule
Sets up 6 days a week.
Report Available
Reports in 2 to 3 days.
Clinical Significance
The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Presumptive positive screen results are reflexed to a more specific and sensitive liquid chromatography mass spectroscopy (LC/MS/MS) test. Therapeutic urine drug monitoring is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.