A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
FISH, B-Cell Chronic Lymphocytic Leukemia Panel, Technical Component
Test Code37885
Preferred Specimen
3 - 5 mL bone marrow or whole blood in sodium heparin (green-top), (royal blue-top) or lead-free (tan-top) tube
Minimum Volume
1 mL
Instructions
Specimen viability decreases during transit. Send specimen to testing lab for viability.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: See Instructions
Refrigerated: See Instructions
Frozen: Unacceptable
Refrigerated: See Instructions
Frozen: Unacceptable
Methodology
Fluorescence In Situ Hybridization (FISH)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
A.M. Sets up 7 days a week.
Report Available
Reports in 5 to 7 days.
Clinical Significance
This test is performed to detect the rearrangements of 6q21 (SEC63), 6q23 (MYB), ATM (11q22.3), centromere 12 (D12Z3), 13q14.3 (DLEU), 13q34 (LAMP1) and TP53 (17p13.1) regions, by FISH (fluorescence in situ hybridization). This assay is useful for prognostic assessment for chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL).